ABSTRACT
Background: Meconium staining of amniotic fluid (MSAF) is a significant risk factor for the subsequent development of meconium aspiration syndrome (MAS), respiratory distress and eventual respiratory failure in neonates. To learn more about the risk factors and outcomes associated with MSAF, a prospective case control study was conducted. The objective of the study was to study various maternal risk factors associated with MSAF and to study the outcome of neonates born through MASF and to compare the perinatal outcome in patients with thick and thin meconium stained amniotic fluid.Methods: A hospital based prospective case control study was conducted comparing pregnant women with meconium stained (cases) amniotic fluid with pregnant women having clear liquor (control), 200 in each arm. Singleton pregnancies complicated with MASF were included in the cases group on the basis of predefined inclusion criteria. Various risk factors, mode of delivery, outcome of neonates and perinatal outcome in babies born through thick and thin meconium stained amniotic fluid was studied.Results: Out of 200 patients who had MSAF 114 patients (57%) had thick meconium stained liquor while remaining 86 patients (43.00%) had thin meconium stained amniotic fluid. Post-maturity, pregnancy induced hypertension; oligohydramnios and prolonged labor were found to be statistically significant risk factors for MSAF. Nonreactive non-stress test and Need for cesarean section was more common in women with MSAF as compared to women with clear liquor (p <0.05). Common morbidities in neonates were Birth asphyxia (15%) followed by meconium aspiration syndrome (10%) and hypoxic ischemic encephalopathy (15%).Conclusions: Meconium stained amniotic fluid is more commonly associated with post-maturity, pregnancy induced hypertension, oligohydramnios and prolonged labor low APGAR score and higher incidence of birth asphyxia and NICU admissions. Appropriate management of neonates with meconium aspiration syndrome is crucial to prevent neonatal mortality.
ABSTRACT
Pelvic inflammatory disease (PID) during late pregnancy is rare. Authors report a case of severe PID manifesting as subacute intestinal obstruction at early third trimester of pregnancy. A 26 years woman at 28 weeks of gestation was admitted in OBG department of Central Referral Hospital (CRH), Sikkim for evaluation of pain in left hypochondrium with tachycardia and mild rise in temperature. Her WBC was 26,900/cmm while urine and blood cultures were sterile. USG showed single live gestation of 27weeks 3days with a heterogeneous mass suggestive of degenerative fibroid. She had recurrent episodes of subacute intestinal obstructions. Her condition deteriorated, hence, elective caesarean with exploratory laparotomy was done. Single live baby was delivered after which abdominal exploration revealed purulent ascites with multiple pockets of pus. Omental cake along with the bowel was adhered to the fundus of uterus. There was no area of perforation in the gut. Bilateral adnexa were adherent to the pre-sacral region which was densely adhered to underlying great vessels. Post operatively antibiotic to cover the anaerobic bacteria were given to which she responded. Baby died after 4 days of birth due to sepsis. One week after discharge she was readmitted with left sided pleural effusion which responded to antibiotics. PID should be considered a cause of abdominal pain and rise in temperature in pregnancy, as early diagnosis can be managed conservatively with antibiotics thus decreasing maternal and perinatal morbidity and mortality.